Ray Peat on vitamin D

Effects of Parathyroid Hormone Increase on Body Tissues

"When vitamin D or calcium is deficient, or when phosphate is excessive, and in hypoglycemia and stress (Ljunghall, et al., 1984), parathyroid hormone increases. This can lead to softening of bones, and hardening of soft tissues, especially arteries, sometimes brain, skin and other organs. Parathyroid hormone increases blood pressure, even before the calcium stiffening is detected."

- September 2017 - Ray Peat's Newsletter

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Calcium and Vitamin D's Effect on Metabolism

"a moderate increase in calcium and vitamin D reduces obesity and increases the metabolic rate, and a fair amount is kno/wn about the mechanisms involved."

- September 2017 - Ray Peat's Newsletter

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Parathyroid Hormone Reduction Linked to Obesity and Related Issues

"The reduction of parathyroid hormone by increased calcium and vitamin D is closely related to reduced obesity, and to the health problems associated with obesity—hypertension, insulin resistance, heart arrhythmias, depression, and various inflammatory conditions."

- September 2017 - Ray Peat's Newsletter

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Aging Skin, Progesterone, and Vitamin D

"It has been known for several decades that the production of progesterone and DHEA decreases steadily with aging, and in recent years it has been noticed that when aged skin is exposed to sunlight it produces only half as much vitamin D as young skin does. Old skin has about half as much cholesterol as young skin, so it isn’t surprising that those substances derived from it are reduced."

- November 2018 - Ray Peat's Newsletter

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Progesterone and Vitamin D in Nerve Function Recovery

"Studies of progesterone’s effects on recovery of nerve function after traumatic brain damage have found that vitamin D increases its effectiveness. By improving calcium homeostasis, opposing the effects of the parathyroid hormone which activates calcium channels, vitamin D (25-hydroxycholecalciferol) is coming to be considered a neurosteroid (Groves, et al., 2014; Gezen-Ak and Dursun, 2019), as well as an essential factor in immunity"

- May 2020 - Ray Peat's Newsletter

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Environmental Factors Potentially Contributing to Autism

"Things in the environment, or substances produced in reactions to environmental stress, that might cause autism, include prenatal and neonatal exposure to radiation, including isotopes from the power industry, bomb testing, Chernobyl, and Fukushima; exposure to air pollution, including nitrogen oxides, ozone, carbon monoxide, sulfur dioxide, and particles (Jung, et al., 2013); aluminum (Mold, et al., 2018), lead, mercury, manganese, arsenic, cadmium, chromium, manganese, and nickel (Windham, et al, 2006); acetaminophen, infections, endotoxin, exogenous and endogenous estrogens, hypothyroidism, progesterone deficiency, agmatine deficiency, serotonin excess, endogenous nitric oxide (Sweeten, et al., 2004), and vitamin D deficiency."

- May 2018 - Ray Peats Newsletter

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Seasonal Variations in Breast Cancer Diagnoses

"There is a clear seasonality in the diagnosis (occurrence) of breast cancer, with a maximum in the spring and a minimum in the fall (Cohen, et al., 1983). The increased discovery in the spring coincides with rising gonadotropins (which are associated with breast and prostate cancer), and the decreased discovery in the fall coincides with higher vitamin D and lower stress hormones."

- May 2016 - Ray Peat's Newsletter

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Common Inhibitors of Carbonic Anhydrase Enzyme

"Among the common inhibitors of carbonic anhydrase are the mildly oxidizing flavonoids such as apigenin and fisetin, some polyphenols, vitamin B1, vitamin D (Mras, et al., 2012), progesterone (partly by blocking the activation by estrogen and aldosterone), and emodin."

- July 2017 - Ray Peat's Newsletter

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Effects of Long-Term Low Vitamin D on Parathyroid Glands

"If your vitamin D was very low for a long time, I think your parathyroid glands probably enlarged, and might take some time to normalize under the influence of a generous amount of vitamin D and calcium."

- Email Response by Ray Peat

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